This triptych shows the scene of lamentation after Christ has been taken down from the cross. In the centre Christ is supported by Joseph of Arimathea, surrounded by St John the Evangelist, the Virgin Mary and Mary Magdalen. Joseph of Arimathea appears again in the left wing of the triptych, accompanied by Nicodemus. The right wing has another representation of Mary Magdalen (holding a covered pot) standing next to an unidentified female saint. The reverses of the wings have representations in grisaille of St John the Baptist and St Barbara respectively.

The appearance of Joseph of Arimathea and Mary Magdalen twice in the scenes of this altarpiece may indicate that the original owner had a personal dedication to these saints.

The artist is unknown. At least three distinct hands appear to have been involved in painting the figures and the continuous landscape background. It is closest in style to the work of the 'Antwerp mannerists'.