The central panel of this triptych depicts the Crowning of the Virgin by the enthroned Christ and God, with assembled saints. On the left wing are twenty three saints including Saints Luke, James the Great, Paul and Mary Magdalene. On the right wing are twenty three saints including Saints Bruno and Barbara. The reverses of the wings show the Annunciation in grisaille (a technique of painting in grey tones to emulate sculpture) with the Virgin on the reverse of the left wing, and the Angel Gabriel on the reverse of the right.

The Master of 1499 is named after the 'Diptych of Christiaan de Hondt' in the Antwerp Museum, which is dated 1499 but is not signed with an artist's name. Several paintings have been attributed to the same artist, who was probably a follower of Hugo van der Goes.